Clinical Descriptive Study of Psoriasis in India: Triggers, Morbidities and Coincidences

Piyu P. Naik*

Clinical Descriptive Study of Psoriasis in India: Triggers, Morbidities and Coincidences.

Psoriasis is a T-cell mediated chronic inflammatory, a papulosquamous
disease involving complex interactions between the innate
and adaptive immune system and commonly manifested by skin lesions.

Chronic psoriasis can be a risk factor for developing comorbid diseases
that share common immune pathophysiology and can be triggered
by environmental factors in genetically susceptible individuals.

To study the clinico-demographic profile, determine the most common
triggering factors and determine comorbidities’ coexistence in patients
with psoriasis at a tertiary care centre.

A teaching hospital-based cross-sectional study including 231 psoriasis
patients visiting skin outpatient department was
conducted by the dermatology department at Sri Krishna hospital, Karamsad, India following acceptance of the study proposal
by the human research ethics committee.

This study was outcome of the dissertation topic of the author during dermatology
residency.

Total 5 qualified dermatologists working in the dermatology department
and 3 resident doctors took part in the study as evaluators.

Data were analysed using statistical package for the social sciences.
factors included stress, winter season, implant insertion, smoking, alcohol
consumption, tobacco chewing and obesity.

Family history was one of the well-established
risk factors for developing psoriasis.

The study shows male preponderance and extensors, trunk as common
sites of psoriatic lesion presentation.

Aggravating factors included stress, winter season, implant insertion, smoking, alcohol consumption, tobacco chewing and obesity.

Psoriasis is a non-contagious chronic inflammatory papulosquamous skin disease
characterized by sharply demarcated erythematous plaques with a whitish scale.

Epidermal proliferation is the earliest pathogenic feature
in psoriasis. There is an increase in deoxyribonucleic acid
synthesis and mitotic activity in the basal layer.

Dermatol Open J. 2021; 6(1): 8-14. doi: 10.17140/DRMTOJ-6-144

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