Hidradenoma Papilliferum.
A 45-year-old female patient presented with an asymptomatic nodule of 6-months duration in the vulva. On examination, a well-circumscribed nodule of size 1 cm was seen on inner aspect of left labium majus (Figure 1).
The nodule was firm and non-tender. Dermoscopy showed pink and white structures with curvilinear vessels (Figures 2 and 3).
Differential diagnoses considered were hidradenoma papilliferum or some other adnexal tumor, pyogenic granuloma, and a remote possibility of donovaniosis or amelanotic melanoma.
The nodule was excised and sent for histopathological examination, which showed a dermal tumor with cells in papillary folds, tubules,
and cystically dilated spaces.
These findings were those of hidradenoma papilliferum.
Hidradenoma papilliferum is an uncommon benign neoplasm arising
from apocrine glands, seen in middle-aged females, commonly
between the ages of 30-49-years.
It usually presents as a firm, flesh to red-coloured nodule in the anogenital area.
The tumor has a good prognosis and malignant transformation is extremely rare.2
The authors have received written informed consent from the patient
The authors declare that they have no conflicts of interest.
Hidradenoma Papilliferum: Pink and White Structures
with Curvilinear Vessels.
Hidradenoma Papilliferum: An Epithelial Proliferation of Tubular
and Acinar Structures Coated by a Double Layer of Abundant Ductal Cells and
Myoepithelial Cells on the Outer Layer.
Differential diagnoses considered were
or some other adnexal tumor, pyogenic granuloma, and a remote possibility
of donovaniosis or amelanotic melanoma.
The nodule was excised and sent for histopathological examination,
which showed a dermal tumor with cells in papillary folds, tubules,
and cystically dilated spaces.
Differential diagnoses considered were, or some other adnexal tumor, pyogenic granuloma.
Dermatol Open J. 2020; 5(1): 10-11. doi: 10.17140/DRMTOJ-5-140
