Low Protein Brown Rice for Preventing Progression of CKD and DKD to End Stage Renal Failure
Chronic kidney disease is pervasive into aging society, affecting permanent
implications on patients’ life. Approximately 10% of the global population has CKD,
and millions die each year.
The prevalence of CKD was high in Latin America, Europe, East Asia and the Middle East,
where approximately 12% of the population has CKD.
Diabetic kidney disease or diabetic nephropathy is a part of CKD when the patients have
diabetes. Both CKD and DKD may progressively fall from a normal estimated glomerular
filtration rate to less than 15, at which point the patient becomes end-stage
kidney disease.
Progression rate of CKD/DKD is recently reported by
Warren et al3 who classified 15,517 participants in the community based
Atherosclerosis Risk in Communities study by diabetes status.
They quantified eGFR trajectories at four visits over 26 years. Adjusted mean eGFR decline
over the full study period among participants without diabetes
was − 1.4 ml/min/1.73 m2 / year, with undiagnosed diabetes was − 1.8 ml/min/year,
and with diagnosed diabetes was − 2.5 ml/min/year.
Over the past 90 years, a protein-restricted diet has been successfully used
to treat chronic renal failure. Recently, the treatment of CKD uses an angiotensin
converting enzyme inhibitor or angiotensin receptor blocker to dilates the glomerular arteriole
for reducing hyperfiltration within the glomerular capillaries.
Low Protein Brown Rice for Preventing Progression of CKD and DKD to End Stage Renal Failure
Diabetes Res Open J. 2018; 4(1): e5-e7. doi: 10.17140/DROJ-4-e012