Marked Enlargement of Liver Over a Short Period of Time

Ichiro Hirukawa, Takeshi Saraya*, Shoko Wada and Hajime Takizawa

Marked Enlargement of Liver Over a Short Period of Time.

An 81-year-old man with Small cell lung cancer, who had been treated
with various intravenous chemotherapies combined with irradiation during
the previous year, was admitted to our hospital
for his third intravenous chemotherapy dose.

Contrast-enhanced thoraco-abdominal computed
tomography on day 1 demonstrated that the primary
lung cancer had not grown; however, multiple new metastatic tumors in the
liver, up to 5 mm in diameter, were seen.

Two weeks later, the liver was markedly
enlarged and repeated Computed
tomography. It demonstrated rapidly
progressing; various sized multiple ring-enhanced
tumors along with evidence of tumor lysis syndrome.

On day 23, he died of multiple organ failure. Liver metastasis is a common
occurrence in lung cancer patients, but the rapid
enlargement of the liver over such a short time period is
an extremely rare phenomenon.

An 81-year-old man with Small cell lung cancer, who had been treated
with various intravenous chemotherapies combined
with irradiation during the previous year,
was admitted to our hospital for his third intravenous chemotherapy dose.

Contrast-enhanced thoraco-abdominal computed tomography
on day 1 demonstrated that the primary
lung cancer had not grown; however, multiple new metastatic tumors in the
liver, up to 5 mm in diameter, were seen.

Two weeks later, the liver was markedly
enlarged and repeated Computed tomography. It demonstrated rapidly
progressing; various sized multiple ring-enhanced tumors along with evidence of tumor
lysis syndrome.

On day 23, he died of multiple organ failure. Liver metastasis is a common
occurrence in lung cancer patients, but the rapid enlargement of the liver over such a short time
period is an extremely rare phenomenon.

Pulm Res Respir Med Open J. 2016; 3(1): 1. doi: 10.17140/PRRMOJ-3-123

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