Rare Localization of Lymphoma.
Primitive Thyroid Lymphomas are rare tumors. Women in the sixth or seventh decade of life are more commonly affected. In the present study, we report a case of primitive thyroid lymphoma and we review the epidemiology, the clinical presentation, the diagnosis, and the treatment of this rare disorder.
A 47-year-old woman presented to our department reporting a recent-onset neck mass since 3 months. Clinical examination revealed an enlargement of the thyroid gland with a 2.5 cm-firm left nodule. Cervical ultrasound was done.
The patient had a thyroidectomy associated with bilateral Central Lymph Node Dissection. The diagnosis was a transformation of a Mucosa-associated lymphoid tissue lymphoma into an aggressive Diffuse Large B-Cell Lymphoma.
The most common type of primary thyroid lymphoma is diffuse large B-cell lymphoma, which behaves in a more aggressive manner than mucosa-associated lymphoid
tissue lymphoma. Treatment and prognosis of PTL depend upon the histology and stage of the
tumor at diagnosis
Primary Lymphoma of the thyroid is a very rare disease. It is less than 2 to 5% of malignant neoplasms of the thyroid.1 Involvement of the thyroid gland may occur in the context of
a systemic disease or rarely be primitive.
The most common histological sub-type is a diffuse
large B-cell lymphoma followed by Mucosa-associated lymphoid tissue lymphoma.
A 47-year-old woman presented to our department reporting a recent-onset neck mass since 3
months. There were no local obstructive symptoms associated such as dyspnea or dysphonia.
Her medical past history was unremarkable. She had no history of personal or family thyroid
disease or radiation exposure. Clinical examination revealed an enlargement of the thyroid
gland with a 2.5 cm-firm left nodule. No cervical nodes were palpable.
Otolaryngol Open J. 2016; 2(3): 91-93. doi: 10.17140/OTLOJ-2-120
