Rationale Diagnostic Criteria of the Metabolic Syndrome.
The increase in obesity over the past 30 years has been fueled by a complex interplay
of unhealthy diet and physical inactivity, environmental, social, economic, and behavioral factors,
acting on a background of genetic susceptibility.
Obesity is a common risk factor for diabetes, hypertension, dyslipidemia and
other lifestyle related diseases, and the preclinical condition has been summarized
under the diagnosis of metabolic syndrome.
The concept of metabolic syndrome was proposed by several committees,
although there had been a considerable disagreement
over the definition and diagnostic criteria.
The above Japanese cutoff point was calculated based on the CT scan data.
In recent years, abdominal computed tomography has become available to determine
the amount of abdominal fat directly and accurately.
In addition, research showed that a goal of at least 7% weight loss from initial
body weight brought by moderate diet and exercise could delay or possibly prevent
type 2 diabetes in nondiabetic people.
The purpose of the cohort study was to identify cancer and cardiovascular disease risks,
and it represented a novel approach that incorporated biological markers as health screening
data, blood, urine, and gene storage for future analyses.
We selected this area because of a long collaborative history for primary
prevention of chronic diseases.
The objective of this study was to examine the validity of diagnostic criteria of metabolic syndrome, especially focusing on the different criteria of waist circumference. We reanalyzed the data of
our previous clinical study and compared the efficacy of SCOP intervention i.e. change in
the rate of metabolic syndrome before and after the intervention
by using the Japanese and IDF criteria.
Diabetes Res Open J. 2019; 5(1): 1-7. doi: 10.17140/DROJ-5-139
