Study of the Central and Peripheral Autonomic Function in Short Evolutions Type 2 Diabetes and it’s Risk Categories.
Early detection of Diabetic Autonomic Neuropathy could help prevent serious complications
and mortality associated with this condition in type 2 diabetes.
We aimed to determine the prevalence of Sudomotor Autonomic Dysfunction,
Cardiac Autonomic Dysfunction in the early stages of glucose metabolism alterations,
ranging from risk categories for type 2 diabetes to recently established type 2 diabetes.
To study autonomic: resting Heart Rate, deep inspiration, controlled breathing, 30/15, Valsalva
maneuver, Sustained handgrip test and prolonged QTc indexes and to study
sudomotor: measurement of the Skin Conductance Response deep inspiration,
controlled breathing, standing to orthostasis, Valsalva maneuver and SHGT.
Obtained results allowed us to determine the order in which every autonomic index passes from
normal to abnormal and the corresponding nerve fibers involved.
Deep inspiration index: significant differences were only found between the
increased risk group and the type 2 diabetes group (p=0.047). 42.9% of the control subjects,
39.1% of the increased risk patients and 59.3% of type 2 diabetes presented anomalous values for this index.
Controlled breathing rate: significant differences were only found between the control
group and the type 2 diabetes group (p=0.008). 7.1% of the control subjects, 31.8% of the increased
risk patients and 34.6% of type 2 diabetes presented anomalous values for this index.
Study of the Central and Peripheral Autonomic Function in Short Evolutions
Type 2 Diabetes and it’s Risk Categories.
Diabetes Res Open J. 2015; 1(1): 12-23. doi: 10.17140/DROJ-1-103
