Using PF-MOUTH GELTM for Sore or Painful Tongue Improved Symptoms and Stabilized Dryness and Trapping of Food: A Case Report

Shuichi Tsubura*, Masahide Kanazawa, Shunya Oka, Rika Hirama and Tsutomu Tsubura

Using PF-MOUTH GELTM for Sore or Painful Tongue Improved Symptoms and Stabilized Dryness and Trapping of Food A Case Report.

The clinical characteristics of sore or painful tongue are well-defined and often involve atrophic glossitis, fissured tongue, median rhomboid glossitis, or burning tongue, although the precise etiology remains unclear or incomplete and definitive treatment has yet to be clarified. The diagnosis, clinical presentation and severity of symptomatic sore or painful tongue are key factors in selecting treatment.

The objectives of treatment are controlling pain, suppressing the inflammatory response, and improving quality of life for the patient. Drug delivery represents a major challenge, because topical medications are easily rubbed or rinsed away from the target area through normal oral movements and salivary flow.

The use of topical corticosteroid ointments for patients with symptomatic sore or painful tongue is expected to control the inflammatory process associated with the formation of symptomatic
sore or painful tongue, but side effects such as burning, changes in taste perception and secondary oral candidiasis may be induced.

Some effectiveness of corticosteroid ointment has been shown in the treatment of symptomatic sore or painful tongue, but has not been satisfactory. Furthermore, treatment for one month or more has been required to reduce symptoms.
Fucoidans are fucose-rich polymers that were identified in brown algae by Kylin in 1918.
Fucoidans have been reported
to show bio-activities such as anti-viral, anti-bacterial, anti-coagulant and anti-tumoral properties. Further, fucoidans have been
used as supplements in cancer patients, and reportedly exert anti-
-inflammatory effects in patients with advanced cancer.

Although,
many studies have attempted to determine the effective of fucoidans as medicines or cosmetics, few have examined
effects on oral diseases.

Dent Open J. 2021; 7(1): 7-11. doi: 10.17140/DOJ-7-143

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